Vagus One. Your body has an off switch. Vagus One feeds it.
The vagus nerve: one nerve from brain to gut, reaching the lungs, heart, stomach and gut.
Rated Excellent on Trustpilot, with three customer reviews.
Built to switch on. It also needs a way back. Vagus One on the calm side.
Yona customer survey: where they felt it first.
It runs on one messenger, made from two pieces, choline and acetyl, plus the energy to join them.
A woman taking a Vagus One capsule, holding the bottle: your nervous system needs nutrition too.
Tired, but still switched on: still awake at 23:42, stomach in knots, 8 hours that feel like 4.
Nine actives, three jobs: Nerve, Signal and State.
Made with doctors and nutritionists: Dr Alisha Damani, David McCollum and Sana Misra.
Two capsules with breakfast, and what to expect week by week.
The Off-Switch Plan: reusable bottle, two refill pouches and a welcome card. Free Welcome Kit included, with the Wind-Down Evenings programme and a WhatsApp nutritionist.
30 days, capsules only.
4.6 from 1,000+ reviews

Vagus One

Daily nutrition for your body's off switch.

Exhausted but wired Stress-reactive digestion Sleep that doesn't restore

New to the vagus nerve? It's the nerve that tells your body the day is over: slow down, digest, recover. When it struggles you feel it as wired nights, a stomach that knots under stress and sleep that doesn't count. Vagus One supplies what it runs on.
The 20-second version ↓

Backed by 40+ peer-reviewed studies. See the science
Choose your plan

That's 93p a day. Less than a coffee.

Ships from the UK · usually 2–3 days

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With the Off-Switch Plan

Your Free Welcome Kit

£35 value · free with 90 days
  1. 1
    3 wind-down habits worth keeping

    A one-page guide to the three habits worth keeping, and permission to drop the rest.

  2. 2
    What to expect, week by week

    What’s normal across your 90 days, so you know you’re on track.

  3. 3
    Your start in the Wind-Down Evenings programme

    How your 90 days run, with a real person checking in at weeks 2, 6 and 12.

Sent by email the day your plan ships, with the WhatsApp number for our clinical nutritionist. Nothing to buy, nothing to cut out.

  • Pause or cancel anytime
  • Third-party tested, every batch
  • Vegan. No fillers or flow agents

“My general regulation — nerves, stomach, sleep — have all improved.”

Jules Z · Verified review
Written and reviewed by the Yona formulation team — not a chatbot, and not medical advice. For anything about your own health, speak to your doctor or pharmacist.
Ingredients

Nine actives. Per 2 capsules:

  • Benfotiamine — 200 mg
  • Thiamine (as thiamine HCl) — 25 mg
  • Riboflavin (as riboflavin-5-phosphate) — 10 mg
  • Magnesium (as magnesium bisglycinate) — 60 mg
  • Citicoline — 250 mg
  • Pantothenic acid (B5) — 100 mg
  • Acetyl-L-carnitine — 300 mg
  • L-theanine — 150 mg
  • Saffron (standardised stigma extract) — 30 mg

Other ingredients: a vegan HPMC capsule, and nothing else. No microcrystalline cellulose, no magnesium stearate, no silicon dioxide.

How to take it

We recommend starting with one capsule a day for the first five days, then moving up to the standard daily dose of two. The gentler start gives your nervous system time to adjust.

  • Best taken with a meal earlier in the day.
  • If you would rather not swallow them, open the capsule and stir the powder into food or any drink.
  • Keep it where you eat, so it isn't a decision.
  • Give it a full 90-day cycle before judging it.

New to the vagus nerve? Read our guide to what it does and how to support it.

What's in it and what's not

Nine actives, independently tested for purity and potency before every batch ships.

Contains
  • Benfotiamine 200 mg + thiamine 25 mg + riboflavin-5-phosphate 10 mg + magnesium (as bisglycinate) 60 mg — the nerve layer
  • Citicoline 250 mg + pantothenic acid 100 mg + acetyl-L-carnitine 300 mg — the signal layer
  • L-theanine 150 mg + saffron 30 mg — the state layer
  • Saffron at 30 mg and citicoline at 250 mg — the amounts used in human research
  • A vegan HPMC capsule — and nothing else
Does not contain
FillersBindersBulking agentsMagnesium stearateMicrocrystalline celluloseSilicon dioxideCaffeineAdded sugarArtificial sweetenersArtificial coloursMelatoninSedativesGlutenDairy
Shipping & returns

Dispatched from the UK with Royal Mail or InPost. Estimated delivery is usually within 2–3 days of dispatch. There is an option for expedited shipping at checkout.

Any questions, message us on WhatsApp or email hello@meetyona.co.uk.

The 90-Day Promise (the Off-Switch Plan). Your 90 days start the day your order arrives. If nothing has changed after taking it every day for the full 90 days, email hello@meetyona.co.uk between day 90 and day 120 and we'll refund what you paid for that supply. No questions to answer and nothing to send back. On a subscription, skip or cancel your next delivery before it bills if you plan to claim.

Explore the science
01 · Yona customer survey

Where they felt it first.

84%

noticed less brain fog and felt sharper

81%

reported better digestion

76%

had more energy through the day

73%

felt calmer and less reactive to stress

Yona customer survey, 2026, self-reported. Individual experiences; results vary. Food supplements are not a substitute for a varied diet or prescribed medication.

In their own words.

Less bloating, less indigestion
The bloating has massively improvedSlowly but surely, by month three
Less of the nervous tummy
Completely settled down
A revelation, after many years
Helped my reflux
A big reduction in my acid reflux
02 · The vagus nerve

Your body has an off switch.

It's called the vagus nerve, and most people have never heard of it. It runs from the base of your brain to your lungs, your heart and your gut, and it's talking to all of them, all day.

  1. (01)

    It's one long nerve.From the base of your brain to your gut. The longest cranial nerve in your body.

  2. (02)

    It's your off switch.Your body switches on when life asks. This nerve tells it the moment has passed: slow the heart, digest the meal, repair overnight. Scientists call it rest and digest.

  3. (03)

    When it struggles, you feel it everywhere.On edge at 11pm. Bloated in a deadline week. Eight hours that feel like four. Not separate problems.

Not four problems. One switch.

Read the full guide to the vagus nerve
Brain Lungs Heart Stomach Gut
Tap an organ

See what the vagus nerve does there.

03 · What flips the switch

One messenger, made from two pieces.

  1. (01)

    Every “stand down” signal your vagus nerve sends is carried by one chemical messenger. It's built from two pieces.

  2. (02)

    Energy joins the two pieces into one messenger. Your body has to keep doing this, all day.

  3. (03)

    The messenger carries the signal, and the switch flips off. Your body can only send what it can make.

CholineAcetyl + energy Stand-down signal
The switch flips off

Vagus One gives your body both pieces, and the energy to put them together.

Scientists call the messenger acetylcholine

Breathwork, cold water

Ask the nerve to fire.

11 methods, compared
Vagus One

Supplies what firing runs on.

04 · The formula

One nervous system. Three layers.

Per 2 capsules30 servingsVegan capsule

A clear crystal cluster on white marble against a pale blue sky
(01) · Four actives

Nerve

The energy to keep sending.

Nutrients selected around normal nervous-system function and neuronal energy.

Benfotiamine200 mg
The fat-soluble form of B1, developed in Japan after chemists found thiamine hiding in garlic. Selected around thiamine-dependent energy metabolism in nerve cells.
Thiamineas thiamine HCl25 mg
Vitamin B1, the first vitamin ever isolated. The standard water-soluble form, working alongside the fat-soluble one.
Riboflavinas riboflavin-5-phosphate10 mg
Vitamin B2, from the Latin flavus, “yellow”. The 5-phosphate form, already activated, selected around energy metabolism in nerve tissue.
Magnesiumas magnesium bisglycinate60 mg
Bound to glycine, the smallest amino acid there is. Chelated for tolerability and selected around normal nervous-system function.
A single white capsule resting on still water
(02) · Three actives

Signal

Both pieces of the messenger.

Built around the nutritional biology involved in acetylcholine signalling.

CiticolineCDP-choline250 mg
The intermediate every cell membrane is built through. Included at 250 mg, the amount used in human research, and selected around the choline side of the signal.
Acetyl-L-carnitine300 mg
Named from the Latin carnis, “flesh”, after chemists first drew it out of muscle in 1905. It carries acetyl groups itself.
Pantothenic acidvitamin B5100 mg
From the Greek pantothen, “from everywhere”. The precursor to coenzyme A, and the acetyl half of that same signal.
A small pile of saffron threads on white marble against a pale blue sky
(03) · Two actives

State

A calmer baseline, without sedation.

Human-studied bioactives selected around calm, the stress response and resilience.

L-theanine150 mg
Isolated from green tea in 1949, and the reason a cup of tea feels nothing like a cup of coffee. Selected to support a settled state without sedation.
Saffronstandardised stigma extract30 mg
Three stigmas per flower, picked by hand: the most expensive spice by weight in the world. Included at the 30 mg used in human research on mood and stress resilience.
The science

Every ingredient earns its place.

Nine ingredients, each chosen from peer-reviewed research for a defined role. Every ingredient, every dose, every reason.

Explore the science behind Vagus One
  • 40+peer-reviewed studies behind the formula
  • 100+years of nervous-system research
  • 19studies in people
A white capsule opened above still water, fine powder falling from it
The capsule

Only what works. Nothing to pad it out.

Most capsules are bulked out with fillers and kept running through the machine with flow and anti-caking agents. Ours hold the nine actives, at full dose, in a plant-based shell. That's all.

  • Nine actives at full doseEvery ingredient at the amount studied, nothing sprinkled in for the label.
  • No fillersNo microcrystalline cellulose to bulk the capsule out.
  • No flow or anti-caking agentsNo magnesium stearate, no silicon dioxide. Our magnesium is bisglycinate.
  • A plant-based shellVegan HPMC capsule. No caffeine, melatonin or sedatives.

Made in a GMP-certified facility

05 · Where it fits

Most approaches cover one layer. Vagus One covers three.

You may already use some of these. They can all be useful. Here's what each one is actually built to reach.

ApproachNerveSignalStateWorth knowing
Magnesium aloneMineralA genuine nervous-system nutrient. It's one of four actives in our nerve layer, not the whole answer.
B-complexVitaminsBroad energy metabolism across the whole body, rather than dosed around neuronal energy.
AdaptogensBotanicalsWork on the stress-hormone response: how hard the system reacts, not what it runs on.
Breathwork, cold, devicesStimulationAn immediate input, in the moment. Keep doing them. They're a different layer, not a rival. See all 11 compared
Vagus OneNervous-system nutritionNine actives across all three layers, daily, from 93p a day. Not a sedative, sleep aid or device.
Built for itPartlyNot what it's for
Reviews

1,000+ reviews. Here's what people keep saying.

4.6
★★★★★

From 1,000+ reviews

“Ten years of gut issues… I’ve tried a lot of different things over the years, and there’s only a handful that I can say made a tangible, measurable difference. The longer I take it, the better I feel.”
YM
Yvonne M.On camera, in her own words
★★★★★Switching off
“I was skeptical that this product could support me, but on reflection my general regulation — nerves, stomach, sleep — have all improved and I’ve felt supported.”
Jules ZVerified buyer · Apr 2026
★★★★★Digestion
“I have been taking these capsules for a few months to try and stop my excessive burping and after the second/third bottle I realised I’d virtually stopped burping completely. I’ve had this problem for YEARS.”
LBMVerified buyer · Jun 2026
★★★★★Switching off
“Before I started taking Yona I would get upset very quickly, now I am more relaxed. I also have more motivation to do things where before I couldn’t be bothered.”
Eileen B.Verified buyer
★★★★★Digestion
“Great product that reduced my acid reflux massively. It took a few months, but I’d had it for years.”
Mary HaleyVerified buyer · Jun 2026
★★★★★Sleep
“The best thing is being able to sleep without the fear of waking up with reflux, and to be able to have a meal and not panic about feeling uncomfortable afterwards.”
Liz H.Verified buyer
★★★★★Recovery
“After suffering fatigue and erratic bowels for weeks after a really aggressive gut bug, Yona really aided recovery… support and reassurance that symptoms would recover in time.”
Philippa RayneVerified buyer · Aug 2026
★★★★★4–5 months in
“I have been using Yona for 4/5 months now and noticed a difference not only in my reflux but my day to day feelings.”
Ben SweeneyVerified buyer · Jun 2026
★★★★★Digestion
“Within the first week I felt a massive difference and have continued using these daily. I have less bloating… Feeling a lot calmer too.”
Kathleen MonaghanVerified buyer · Aug 2024
★★★★★Digestion
“I was suffering from acid reflux very often, sometimes I was choking in the middle of the night… I can eat anything I want without thinking about acid reflux. My digestion feels better.”
Saintia MapukuVerified buyer · Apr 2026
★★★★★Digestion
“I have been taking it for nearly a month and I can feel the difference… less bloating, and don’t seem to get any acid indigestion.”
Sally S.Verified buyer
★★★★★Honest take
“My symptoms have definitely improved. I’m now symptom free for the majority of the time… Don’t expect a fast cure but I do think it helps.”
SaraVerified buyer · May 2026

Reviews from Yona customers, including Vagus+, the formula Vagus One grew out of. Trimmed for length where marked; otherwise in the words they were written in.

Verified

Reviews from Yona users.

Previously called Vagus+ — the formula Vagus One grew out of.

Two Vagus One capsules in an open palm at a breakfast table, the bottle, a coffee and a glass of water behind
06 · The 90-day routine

Ninety days. One simple routine.

Nervous-system nutrition is a daily practice, not a quick fix. Vagus One is designed to be taken every day, which is why the Off-Switch Plan is 90 days, backed by the 90-Day Promise.

Days 1–5 1 capsule with a mealFrom day 6 2 capsules, same mealTip Open one into food or a drink

  1. WEEKS 1–2

    Laying the foundation.You're supplying raw materials, not taking a sedative. The only job is not missing days.

  2. WEEKS 3–4

    The evening goes first.Where people notice something, it tends to show up at night. 64% of those who noticed a change did so within four weeks.

  3. MONTH 2

    It stops being a decision.The capsules are part of a meal, not a task. What changes tends to arrive as a new baseline, not an event.

  4. MONTH 3

    A settled routine.A pattern that took years to set doesn't shift in three weeks. Ninety days gives a daily routine time to become your baseline, and it's covered by the 90-Day Promise.

It's for you if…

  • You get to the end of the day and still can't come down.
  • Your digestion tracks your stress a little too closely.
  • You sleep the hours but don't wake up restored.
  • You already breathe, plunge or hum, and want the other half of it.
Read the signs of low vagal tone

It's not for you if…

  • You want something that knocks you out. No melatonin, no sedatives.
  • You want to feel it by Friday. This is cumulative.
  • You expect it to fix a diagnosed condition. It's food, not treatment.
  • You're pregnant, breastfeeding, under 18 or on prescription medication. Ask your doctor first.
07 · Who's behind it

The people behind it. And the clinicians who check it.

Dr Alisha DamaniDr Alisha DamaniMBChB · Clinical advisor

Specialises in autonomic nervous system function and its effect on digestive health, the exact biology Vagus One is built around. Her role is the reality check.

David McCollumDavid McCollumCert Nat ANP · Clinical nutritionist

Twenty-five years in clinical nutrition, working in complex digestive dysfunction and nervous-system recovery. He brings the casework.

Sana MisraSana MisraAdvisor · Former NHS doctor

As a doctor in the NHS she kept seeing the same pattern: digestion that changed with stress, sleep that fell apart when people couldn’t unwind. That question led to Yona.

Developed with a medical and clinical advisory team spanning medicine and nutrition.

08 · The guides

Learn more about the vagus nerve.

All guides
  1. (01)

    The vagus nerveWhat it does, the signs it's struggling, and how to support it.

  2. (02)

    Signs of low vagal toneWhat it feels like day to day, and what actually helps.

  3. (03)

    11 ways to stimulate it, comparedBreathing, cold, devices and more, ranked by the evidence.

  4. (04)

    The vagus nerve and digestionHow your gut and brain talk, and why stress lands in your stomach.

09 · Before you decide

The questions people actually ask.

  1. (01)

    Pause or skipPush a delivery back or skip it. Your price doesn't change.

  2. (02)

    Cancel in one clickNo minimum term, no fee, nobody to persuade.

  3. (03)

    Or don't subscribeBuy a single supply. Subscribing is a discount, not a requirement.

Still unsure? WhatsApp us or email hello@meetyona.co.uk.

Does Vagus One stimulate the vagus nerve?

No. Breathwork, cold and devices stimulate it: they ask it to fire. Vagus One is nutrition. It supplies nutrients and bioactives selected around the biology the nerve runs on. Stimulation is one layer; nutrition is another, and we'd rather you did both. Compare the 11 stimulation methods.

What's the science behind Vagus One?

Over a century of nervous-system science, curated into one formula. Every ingredient was chosen from peer-reviewed research, more than 40 studies in all, and each has a defined role across Nerve, Signal and State. Explore the science.

Who is it designed for?

People who recognise the feeling: “My body struggles to switch off.” Tired but still on, stress-reactive digestion, restless evenings, sleep that doesn't restore. A body that's very good at switching on, and struggles to switch back. Read the signs of low vagal tone.

Why not just take magnesium?

Magnesium is in it: 60 mg, as bisglycinate. But it's one of nine. Vagus One pairs it with the B-vitamin, choline and calm-state layers, rather than relying on one ingredient alone. If magnesium on its own already helps you, that's a reason to expect more here, not less.

Why are there no fillers or flow agents in it?

Most capsules carry microcrystalline cellulose, magnesium stearate and silicon dioxide: a filler, a lubricant and an anti-caking agent. They make manufacturing faster. They do nothing for you, and early research has started asking questions about them, silicon dioxide and the gut in particular. Vagus One has none of the three: nine actives in a vegan capsule, and nothing else.

Will it make me sleepy or wired?

Neither. There's no melatonin, valerian or caffeine. It's a daily foundation, not something that knocks you out or gives you a buzz. The State layer, L-theanine and saffron, is there so it never feels like a stimulating nootropic.

How quickly will I notice something?

Most people who notice a change feel it within the first three to four weeks, usually in the evening first. It builds from there, which is why Vagus One is designed as a 90-day routine, and your first 90-day supply is backed by the promise.

What if I'm sensitive to supplements?

Take it gradually: one capsule a day for the first five days, then two when you're ready. You can also open a capsule into food or a drink. If you're unsure at any point, message us.

Can I take it alongside medication?

Ask your doctor or pharmacist first, particularly if you take prescribed medication, are pregnant or breastfeeding, or have an existing condition. Take the bottle with you. Never stop or reduce prescribed medication because you've started a supplement.

How does the subscription work?

The 30-day arrives monthly, the 90-day every three months. It's cheaper because a predictable order costs us less to fulfil. There's no minimum term: pause, skip or cancel from your account, without emailing anyone.

How long does delivery take?

Dispatched from the UK with Royal Mail or InPost, usually within 2–3 days, with expedited shipping available at checkout.

What’s in the Free Welcome Kit?

It comes by email the day your Off-Switch Plan ships: our one-page guide to the 3 wind-down habits worth keeping (and permission to drop the rest), and what to expect week by week across your 90 days. Nothing to buy, nothing to cut out. It comes with both 90-day options.

What is the Wind-Down Evenings programme?

A 90-day programme for Off-Switch Plan members, built around your evenings: short, practical tips at the moments that matter, with a real person checking in with you at weeks 2, 6 and 12.

Who answers the WhatsApp line?

A clinical nutritionist from the Yona team, 6 days a week. A real person, not a bot. Ask about how to take Vagus One, food, timing and your routine. They don’t diagnose or change anything you’ve been prescribed. The number comes in your welcome email, with both 90-day options.

Will my price go up?

Not while you stay subscribed. The price you start the Off-Switch Plan at is the price of every delivery after it, even if our prices change later. If you cancel and come back, you’d pay the price at that time.

Vagus One

The Off-Switch Plan: the Vagus One bottle, two kraft refill pouches and a welcome card on a stone plinth in the sky
The Off-Switch Plan

90 days to a body that knows when the day is over.

  1. WELCOME KIT

    Free with 90 days: the guide, week by week, and a nutritionist on WhatsApp.

  2. 4.6 ★

    From 1,000+ reviews.

  3. PROMISE

    Nothing changed after 90 days? One email gets every penny back.

£28a month · £84 every 3 months · cancel anytime

Vagus One